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Thursday, July 16, 2020 | History

1 edition of Coronary artery stents in the treatment of ischaemic heart disease found in the catalog.

Coronary artery stents in the treatment of ischaemic heart disease

Coronary artery stents in the treatment of ischaemic heart disease

a rapid and systematic review

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  • 26 Currently reading

Published by Core Research on behalf of the NCCHTA in Alton .
Written in English


Edition Notes

StatementC. Meads ... [et al.].
SeriesHealth technology assessment -- v.4, no.23
ContributionsMeads, Catherine., National Co-ordinating Centre for HTA (Great Britain)
The Physical Object
Paginationvi, 153p. :
Number of Pages153
ID Numbers
Open LibraryOL19674476M

  Coronary heart disease refers to a mismatch between myocardial oxygen supply and demand. Atherosclerosis is the most important cause. Atherosclerotic changes in coronary vessel walls lead to a narrowing of the lumen and prevent vessels from dilating. As a result, an increase in oxygen demand (e.g., during physical activity) can no longer be satisfied and/or myocardial perfusion at rest is. Ischemic heart disease is also known as coronary artery disease or "hardening of the arteries." Cholesterol plaque can build up in the arteries of the heart and cause "ischemia," which means the heart is not getting enough blood flow and oxygen. If the plaque blocks an artery, a heart .

Start studying Patho Ischemic Heart Diseases. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Regardless of maximal pharmacotherapy and conventional revascularisation, up to 15% of patients with end-stage coronary artery disease suffer from disabling symptoms. 1 In addition, there is a lack of donors for heart transplants, which increases the need to offer viable alternatives for patients in the future. Recently, cell therapy has Author: Hans-Michael Klein.

Coronary artery disease (CAD), also known as coronary heart disease (CHD), ischemic heart disease (IHD), or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of plaque in the arteries of the heart. It is the most common of the cardiovascular diseases. Types include stable angina, unstable angina, myocardial infarction, and sudden cardiac death.   A recent meta-analysis performed comparing revascularization type based on lesion location noted that coronary restenosis/failure occurred more often with endovascular intervention than with open surgical approach (Odds ratio , 95% CI , p = ). 18 While conventional coronary artery bypass grafting, patch angioplasty and.


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Coronary artery stents in the treatment of ischaemic heart disease Download PDF EPUB FB2

Background: Coronary artery stents are prosthetic linings inserted into coronary arteries via a catheter to widen the artery and increase blood flow to ischaemic heart muscle.

They are used in the treatment of ischaemic heart disease (IHD). IHD is a major cause of morbidity and mortality (, deaths per annum) in the UK and a major cost to the by:   Coronary heart disease, or ischemic heart disease, includes heart problems caused by narrowed heart arteries, which in turn result in less blood and oxygen reaching the heart muscle.

It can ultimately lead to a heart attack, known clinically as a myocardial infarction (MI). ISCHEMIA is not the first study to demonstrate that OMT is a safe and effective alternative to stent placement. But it is the most influential because of its careful design, large number of patients, and comparison of the newest stents and most current medical treatments.

So, how best to manage patients with stable coronary artery disease. Coronary or Ischaemic Heart Disease Health Plan Q: After experiencing angina 4 years ago, angioplasty revealed a 95%+ blockage in my right coronary artery and a stent was inserted.

That has worked fine and my life has been pretty normal since then – I’m quite active, walking, swimming and in general good health. Coronary artery disease (CAD) is a major cause of death and disability in developed countries. Although coronary artery disease mortality rates worldwide have declined over the past decades, CAD remains responsible for about one third or more of all deaths in individuals over the age of 35 years.

Various methods of treatment have been proposed including medical therapy, catheter. Percutaneous coronary intervention (PCI) has been rapidly evolving since its initial application in Over the years, it has become a mainstay of the treatment of coronary artery disease, including acute coronary syndromes and stable ischemic heart disease.

With the advent of novel ancillary technologies, such as intravascular ultrasound (IVUS) and optical coherence. Most ischaemic heart disease is caused by atherosclerosis, usually, present even when the artery lumens appear normal by angiography.

Initially, there is sudden severe narrowing or closure of either the large coronary arteries and/or of coronary artery end. A coronary stent is a tube-shaped device placed in the coronary arteries that supply blood to the heart, to keep the arteries open in the treatment of coronary heart is used in a procedure called percutaneous coronary intervention (PCI).

Coronary stents are now used in more than 90% of PCI procedures. Stents reduce angina (chest pain) and have been shown to improve survivability and. The use of dual antiplatelet therapy (DAPT) after stent implantation in a percutaneous coronary intervention (PCI) is the standard treatment.

The first randomised controlled trial (RCT) to establish the superiority of DAPT versus oral anticoagulant treatment among patients undergoing PCI was the Intracoronary Stenting and Antithrombotic Regimen (ISAR) trial, published in 1 Since.

Meads C, Cummins C, Jolly K, Stevens A, Burls A, Hyde C. Coronary artery stents in the treatment of ischaemic heart disease: a rapid and systematic review. Health Technology Assessment ; 4(23): [PubMed: ].

In people with coronary heart disease and ischemia, adding angioplasty to drug treatment does not reduce cardiovascular events. Stergiopoulos K, Boden WE, Hartigan P, et al.

Percutaneous coronary intervention outcomes in patients with stable obstructive coronary artery disease and myocardial ischemia: a collaborative meta-analysis of contemporary randomized clinical trials. This creates a new path for blood to flow around (bypass) the blockage in the artery so it can get to your heart.

Patients undergoing bypass are put under general anaesthetic and are not awake during surgery. Two bypass surgical procedures for coronary artery disease are: (1) beating heart surgery and (2) arrested heart surgery. Chevalier B, Onuma Y, Boven AJ Van.

Randomised comparison of a bioresorbable everolimus- eluting scaffold with a metallic everolimus-eluting stent for ischaemic heart disease caused by de novo native coronary artery lesions:the 2-year clinical outcomes of the ABSORB II trial. EuroIntervention. ; Alvarez M, Applegate RJ. Significant left main coronary artery disease is defined as a greater than 50% angiographic narrowing of the vessel.

In general, there are three options for the treatment of LMCA disease which include optimal medical therapy, percutaneous revascularization, or surgical revascularization, either off-pump or on-pump. It is the highest-risk lesion subset of ischemic heart disease. In developed countries, coronary artery disease is the leading cause of death in both sexes, accounting for about one third of all deaths.

Mortality rate among white men is about 1/10, at ages 25 to 34 and nearly 1/ at ages 55 to Mortality rate among white men aged 35 to 44 is times.

Stable ischemic heart disease (SIHD) is a highly prevalent condition associated with increased costs, morbidity, and mortality. Management goals of SIHD can broadly be thought of in terms of improving prognosis and/or improving symptoms. Treatment options include medical therapy as well as revascularization, either with percutaneous coronary intervention or coronary artery bypass grafting.

Ischemic means that an organ (e.g., the heart) is not getting enough blood and oxygen. Ischemic heart disease, also called coronary heart disease (CHD) or coronary artery disease, is the term given to heart problems caused by narrowed heart (coronary) arteries that supply blood to the heart muscle.

Coronary artery disease. Coronary artery disease, also called ischaemic heart disease, happens when the major blood vessels in the heart get narrow and stiff.

It can cause heart attacks and angina. Read about its symptoms, causes and its treatment. Coronary artery disease (CAD) is the most common kind of heart disease.

Heart Attack - Treatment. Various medications can help break up artery clots and can reduce heart damage, widen blood vessels, decrease pain and help regulate heart rhythm. Procedures can open up narrowed or blocked arteries (angioplasty or stents).

In severe cases, bypass surgery is performed to restore the heart’s blood supply. The management of ST-segment elevation acute coronary syndrome (STEACS) is based on the quick opening of the culprit artery through the use of fibrinolytic drugs or a percutaneous coronary intervention (PCI) that limits the size of the infarction and improves prognosis.1 Fibrinolytic drugs have proven capable of increasing survival,2 but they.

Coronary heart disease, or ischemic heart disease, includes heart problems caused by narrowed heart arteries, which in turn result in less blood and oxygen reaching the heart muscle. It can ultimately lead to a heart attack, known clinically as a myocardial infarction (MI).

Coronary heart disease is the most common cardiovascular ailment. Coronary heart disease (CHD) is a leading cause of death in Western countries and is increasingly common in developing countries. This atherosclerotic process includes injury to arterial endothelium, fatty streaks due to macrophage ingestion of oxidized LDL cholesterol at the damaged site, platelet aggregation, and fibrosis.Sensitivity to acetylsalicylic acid (ASA) is important in the treatment of patients with coronary heart disease (CHD) after coronary artery bypass grafting (CABG).

Patients were divided into ASA sensitive (sASA) and ASA resistant (rASA) by the activity of platelet aggregation induced arachidonic acid (ARA) together with ASA.